Invite to talk on Epigenetics of Adaptation

Epigenetics of Adaptation. A talk by Dr Chris Murgatroyd on Thursday March 30 at 6pm in T0.03, John Dalton building. (Refreshments available from 5.30pm).

 Adverse conditions during childhood can increase vulnerability to mood disorders later in life. During early life the brain exhibits high plasticity, which allows environmental signals to shape the experience-dependent maturation of stress-regulating pathways leading to long-lasting altered stress responsivity during adulthood. Current research addressing the mechanisms is showing that epigenetic factors can program the activity of genes in response to an environment that in turn can give rise to persistent alterations of adult physiology and dysfunction eventually leading in disease.

In this talk, Chris Murgatroyd will address recent research in the field of epigenetic programming in psychiatry discussing links between animal models and human studies, transgenerational effects and gene-environment interactions towards the development of personalised approaches in healthcare.

Chris Murgatroyd has a BSc in Genetics (Swansea), an MSc in Medical Genetics (Newcastle) and PhD in Psychiatric Genetics (Munich) and is now a Reader at Manchester Metropolitan University. Working as a postdoctoral scientist at the Max Planck Institute of Psychiatry he identified epigenetic changes controlling neuroendocrine regulation of behaviour in mice exposed to early-life stress. Since being at Manchester Metropolitan University he has been studying the role of early-environment on epigenetic changes in humans and animal models.

Refreshments will be available from 5.30pm in the John Dalton building, with the talk beginning in Lecture Theatre T0.03 at 6pm. This will last around one hour and will include time for audience questions. The event will finish with a drinks reception and further discussion.

Attendance to this event is free of charge, however we do ask that you book tickets in advance at

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